1 May 2007 Study of a new parameter used in objective measurement of skin erythema
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Proceedings Volume 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine; 653413 (2007) https://doi.org/10.1117/12.741476
Event: Fifth International Conference on Photonics and Imaging in Biology and Medicine, 2006, Wuhan, China
Abstract
The objective measurement of skin erythema is of much importance in clinical dermatological diagnosis and new dermatological drug tests. The measurements that used currently are facing a main problem that all the measurements are deeply influenced by the melanin in the epidermis and the incident intensity. Basing on the skin optical model, a new parameter is introduced in order to describe the change of erythema. The new parameter is defined by the difference of the logarithm of the diffuse reflected light intensity between normal skin and erythema skin. The theoretical analysis shows that this new parameter can reflect directly the deviation of the concentration of haemoglobin from the normal range under the assumption of keeping the concentration of melanin constant and the illuminating light uniform. In addition, the experimental study also shows that this method is hardly influenced by the illuminating light intensity, and can be effectively applied in the clinical diagnosis.
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Keke Shang, Keke Shang, Ying Liu, Ying Liu, Yixing Lu, Yixing Lu, Yu Guo, Yu Guo, Lijun Wang, Lijun Wang, Xiaoqi Chang, Xiaoqi Chang, } "Study of a new parameter used in objective measurement of skin erythema", Proc. SPIE 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine, 653413 (1 May 2007); doi: 10.1117/12.741476; https://doi.org/10.1117/12.741476
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