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26 April 2007Frequency-domain photon density wave setup with multicolor illumination at 684, 794, and 1060 nm
An experimental setup for multicolor frequency-domain optical diffuse tomography was designed to visualize soft
biological tissue inhomogeneities at the distance of up to 6 cm. Scanning is performed by independent electronically
controlled shift of source and detector placed in transmission mode. Employing illumination at three wavelengths (684,
794, and 1060 nm) which correspond to predominating absorption of oxygenated hemoglobin, deoxygenated
hemoglobin and water provides determination of component composition of an inhomogeneity. Source power
modulation at 140 MHz increases spatial resolution (compared to CW imaging) and improves quality of reconstruction
procedure. Studies on model media and preliminary in vivo experiments were performed.
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Vladimir I. Plehanov, Ilya V. Turchin, Ekaterina A. Sergeeva, Vladislav A. Kamensky, "Frequency-domain photon density wave setup with multicolor illumination at 684, 794, and 1060 nm," Proc. SPIE 6535, Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII, 653508 (26 April 2007); https://doi.org/10.1117/12.740608