Frequency-domain photon density wave setup with multicolor illumination at 684, 794, and 1060 nm

Vladimir I. Plehanov; Ilya V. Turchin; Ekaterina A. Sergeeva; Vladislav A. Kamensky

doi:10.1117/12.740608

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26 April 2007 Frequency-domain photon density wave setup with multicolor illumination at 684, 794, and 1060 nm

Vladimir I. Plehanov; Ilya V. Turchin; Ekaterina A. Sergeeva; Vladislav A. Kamensky

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Proceedings Volume 6535, Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII; 653508 (2007) https://doi.org/10.1117/12.740608
Event: Saratov Fall Meeting 2006, 2006, Saratov, Russian Federation

Abstract

An experimental setup for multicolor frequency-domain optical diffuse tomography was designed to visualize soft biological tissue inhomogeneities at the distance of up to 6 cm. Scanning is performed by independent electronically controlled shift of source and detector placed in transmission mode. Employing illumination at three wavelengths (684, 794, and 1060 nm) which correspond to predominating absorption of oxygenated hemoglobin, deoxygenated hemoglobin and water provides determination of component composition of an inhomogeneity. Source power modulation at 140 MHz increases spatial resolution (compared to CW imaging) and improves quality of reconstruction procedure. Studies on model media and preliminary in vivo experiments were performed.

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Vladimir I. Plehanov, Ilya V. Turchin, Ekaterina A. Sergeeva, and Vladislav A. Kamensky "Frequency-domain photon density wave setup with multicolor illumination at 684, 794, and 1060 nm", Proc. SPIE 6535, Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII, 653508 (26 April 2007); https://doi.org/10.1117/12.740608

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