26 April 2007 Monte Carlo study of skin optical clearing to enhance light penetration in the tissue
Author Affiliations +
Abstract
Result of Monte Carlo simulations of skin optical clearing is presented. The model calculations were carried out with the aim of studying of spectral response of skin under immersion liquids action and calculation of enhancement of light penetration depth. In summary, we have shown that: 1) application of glucose, propylene glycol and glycerol produced significant decreasing of light scattering in different skin layers; 2) maximal clearing effect will be obtained in case of optical clearing of skin dermis, however, absorbed light fraction in skin dermis changed insignificantly, independently from clearing agent and place it administration; 4) in contrast to it, the light absorbed fraction in skin adipose layer increased significantly in case of optical clearing of skin dermis. It is very important because it can be used for development of optical methods of obesity treatment.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Alexey N. Bashkatov, Elina A. Genina, Valery V. Tuchin, Mikhail M. Stolnitz, Dmitry M. Zhestkov, Jürgen M. Lademann, "Monte Carlo study of skin optical clearing to enhance light penetration in the tissue", Proc. SPIE 6535, Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII, 653514 (26 April 2007); doi: 10.1117/12.740977; https://doi.org/10.1117/12.740977
PROCEEDINGS
12 PAGES


SHARE
RELATED CONTENT

Tissue image contrasting using optical immersion technique
Proceedings of SPIE (October 11 2000)
Tissue structure analysis at optical immersion
Proceedings of SPIE (September 12 2002)
Immersion effects in tissues
Proceedings of SPIE (November 03 2000)
Controlling optical properties of bio tissue by the use of...
Proceedings of SPIE (February 08 2007)

Back to Top