Biomedical application of laser-induced tissue oxygenation

M. M. Asimov

doi:10.1117/12.727222

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13 March 2007 Biomedical application of laser-induced tissue oxygenation

M. M. Asimov

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Proceedings Volume 6604, 14th International School on Quantum Electronics: Laser Physics and Applications; 660428 (2007) https://doi.org/10.1117/12.727222
Event: 14th International School on Quantum Electronics: Laser Physics and Applications, 2006, Sunny Beach, Bulgaria

Abstract

Concentration of oxygen in tissue plays an important role in enhancing in vivo wide variety of biochemical reactions including cell metabolism. Aerobic cell metabolism is primary mechanism in energy production in tissue. Controlling this mechanism gives unique possibility of biological stimulation to reach therapeutic effect. This goal could be reached by laser-induced photodissociation of oxyhemoglobin in cutaneous blood vessels. This phenomenon is considered as a main mechanism of biostimulating and therapeutic effect of low energy laser radiation. Laser-induced photodissociation of oxyhemoglobin in vivo manifests itself through the changes of the value of arterial blood saturation before and during the laser irradiation. High sensitive pulse oxymeter could be used for the measurements of the level of arterial blood saturation. Unique possibility is reached in local increase the concentration of oxygen by additional releasing it into tissue. Laser-induced enrichment of tissue oxygenation stimulates of cell metabolism and allows develop new effective methods for laser therapy as well as phototherapy of pathologies where elimination of local tissue hypoxia is critical.

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M. M. Asimov "Biomedical application of laser-induced tissue oxygenation", Proc. SPIE 6604, 14th International School on Quantum Electronics: Laser Physics and Applications, 660428 (13 March 2007); https://doi.org/10.1117/12.727222

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