Virtual Endoscope is a method to emulate cavity checking visually combined row volume data obtained from CT and
MR with three-dimensional image technologies in virtue of navigation, flythrough and pseudo-color technologies. The
application on virtual endoscope is developed in recent several years, and the software realization needs the support of multiple complicated algorithms, including internal surface reconstruction, center path automatic extraction, lens setting-up, multi-case processing, collision detection, and corresponding algorithm computation and realization, which cause the application software development for Virtual Endoscope is rather complex and difficult. It puts forward volume rendering for rapid three-dimensional reconstruction, introduces highly active path planning algorithm of three-dimensional space path algorithm, improved path smooth algorithm and lens entry point auto-detecting algorithm, illustrates three-dimensional scene establishment by VTK development toolkit, and discusses the key technologies in virtual endoscope realization in this paper, based on which the virtual endoscope system has graceful performance.