13 July 2007 High throughput high content live cell screening platform
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The goal was to develop a light-microscope platform concept, which allows characterization of live cells in microtiter plates or in live-cell slide chambers with a speed, sensitivity and versatility unattainable so far. The goal was achieved by combining several novel technological concepts: a model-based digital control for a voice coil focus drive; scanner technology to follow a continuously moving sample during image acquisition, thus avoiding the usual stop-and-go; fast sectioning capabilities by using slit-scan confocal concepts; motorized dual emission image registration; and integrated environmental control.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Rainer Uhl, Rainer Daum, Hartmann Harz, Christian Seebacher, Schomiron Neogy, "High throughput high content live cell screening platform", Proc. SPIE 6633, Biophotonics 2007: Optics in Life Science, 66330C (13 July 2007); doi: 10.1117/12.729545; https://doi.org/10.1117/12.729545

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