A new SPR sensing technique using a chip with a fabricated microstructure

Hiroki Okuno; Fumikazu Oohira; Nobumitsu Miyanishi; Seiko Shimamoto; Maho Hosogi

doi:10.1117/12.754374

10 October 2007 A new SPR sensing technique using a chip with a fabricated microstructure

Hiroki Okuno, Fumikazu Oohira, Nobumitsu Miyanishi, Seiko Shimamoto, Maho Hosogi

Proceedings Volume 6717, Optomechatronic Micro/Nano Devices and Components III; 67170U (2007) https://doi.org/10.1117/12.754374
Event: International Symposium on Optomechatronic Technologies, 2007, Lausanne, Switzerland

Abstract

In this study, we proposed a new sensing method using a special SPR chip on which microstructures are fabricated, and performed a principle confirmation of the sensing feasibility using this chip. We examined a fabrication method of micro structures on the SPR chip that has a filter effect by the pillar structure, which can filter the target substance reaching to the detection area of SPR sensing. In order to confirm the filter effect of the micro structure on the SPR chip, we performed the principle confirmation experiment of the SPR sensing system using the fine particles. Next, in order to adapt to the biological molecules measurement, we performed the experiment using yeast cells and demonstrated the filter effect of this chip with the micro structure.

Citation Download Citation

Hiroki Okuno, Fumikazu Oohira, Nobumitsu Miyanishi, Seiko Shimamoto, and Maho Hosogi "A new SPR sensing technique using a chip with a fabricated microstructure", Proc. SPIE 6717, Optomechatronic Micro/Nano Devices and Components III, 67170U (10 October 2007); https://doi.org/10.1117/12.754374

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