The charge variable range hopping mechanism is used to study the charge conduction in biomaterials such as DNA. We have considered that the charge particles are localized in bases of DNA nucleotides and nucleosides. The H-bonds and pi-pi bonds between the bases couple the two strands together and this structure is ideal for electron transfer due to hopping mechanism. The electron orbital belonging to the bases overlap quite well with each other along the long axis of the DNA. A DNA helix with random base couple sequence can be viewed as one dimensional disordered system. The charge carriers are localization in bases due the disorder in the system and the localization is enhanced by strong thermal fluctuations (i.e. phonons) in these structures. The interaction between localized carriers and phonons create polarons which are responsible for charge conduction in DNA due to the variable range hopping mechanism. Numerical simulations are performed for different type of DNA structures such as ribbons and films. A good agreement between our simulations and experiment is found.