You have requested a machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Neither SPIE nor the owners and publishers of the content make, and they explicitly disclaim, any express or implied representations or warranties of any kind, including, without limitation, representations and warranties as to the functionality of the translation feature or the accuracy or completeness of the translations.
Translations are not retained in our system. Your use of this feature and the translations is subject to all use restrictions contained in the Terms and Conditions of Use of the SPIE website.
8 January 2008Dynamic OCT for physiological functions of micro organs in human fingers
OCT is a powerful tool for detection of physiological functions of micro organs underneath the human skin
surface, besides the clinical application to ophthalmology, as recently demonstrated by the authors' group. In
particular, dynamics of peripheral vessels and eccrin sweat glands can be observed clearly in the
time-sequential OCT images. The physiological functions of these micro organs, sweating and blood
circulation, are controlled by the skin sympathetic nerve in response to externally applied stress. In this paper,
we present microscopically analytical results based on the dynamic OCT of the micro organs in human
fingers. In sweating dynamics, it is found that a spiral sweat duct is expanded by abrupt increase of sweat
due to application of stress to a volunteer, resulting in remarkable increase of the reflection light intensity of
the spiral duct in OCT. Mental-stress-induced sweating in each eccrin sweat gland, therefore, is analyzed
quantitatively. Furthermore, dynamic OCT observation of peripheral vessels is interesting. A small vein of a
human finger is observed clearly by the TD-OCT, where the vein expands and contracts repeatedly even in
the resting state for temperature control on the fingertip. A change in the cross-sectional area of the vein
exceeds 80 % for a young volunteer. The dynamic OCT will allow us to propose novel diagnoses of
excessive sweating and diseases related to the sympathetic nerve.
The alert did not successfully save. Please try again later.
Masamitsu Haruna, Masato Ohmi, Yoshihiro Ueda, Toshie Fuji, Akihiro Yamada, Hiroyuki Saigusa, Mitsuo Kuwabara, "Dynamic OCT for physiological functions of micro organs in human fingers," Proc. SPIE 6826, Optics in Health Care and Biomedical Optics III, 682603 (8 January 2008); https://doi.org/10.1117/12.754644