Paper
8 January 2008 Novel coherent anti-stokes Raman scattering microscopy for high contrast bioimaging
Author Affiliations +
Abstract
Conventional polarization coherent anti-Stokes Raman scattering (P-CARS) microscopy always suffers from serious signal attenuation in imaging cells and tissue. We develop a novel heterodyne-detection method for P-CARS imaging with an ability of high imaging vibrational contrast and signal strength. We demonstrate this method by imaging 4.69-μm polystyrene beads immersed in water.
© (2008) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Fake Lu, Wei Zheng, and Zhiwei Huang "Novel coherent anti-stokes Raman scattering microscopy for high contrast bioimaging", Proc. SPIE 6826, Optics in Health Care and Biomedical Optics III, 68260Y (8 January 2008); https://doi.org/10.1117/12.755556
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KEYWORDS
Polarization

Microscopy

CARS tomography

Signal detection

Medical research

Tissues

Beam splitters

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