8 January 2008 Surface-enhanced Raman spectroscopy of urine by an ingenious near-infrared Raman spectrometer
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Abstract
This paper demonstrates the potential of an elaborately devised near-infrared Raman system in analysis of urine. The broad band in the long-wavelength region of the electronic absorption spectra of the sol with added adsorbent at certain concentrations has been explained in terms of the aggregation of the colloidal silver particles. We have reported the surface-enhanced Raman (SERS) spectra of urine, and studied the silver solution enhanced effects on the urine Raman scattering. The Raman bands of human's urine was assigned to certain molecule vibrations. We have found that different donators have dissimilar SERS of urine in different physiological condition. Comparatively few studies have explored the ability of Raman spectroscopy for the analysis of urine acid. In the present report, we investigated the ability of surface enhanced Raman spectroscopy to measure uric acid in the human urine. The results suggested that the present Raman system holds considerable promise for practical use. Practical applications such as the quantitative medical examination of urine metabolites may also be feasible in the near future.
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Shangyuan Feng, Weiwei Chen, Yongzeng Li, Guannan Chen, Zufang Huang, Xiaohua Liao, Zhiming Xie, Rong Chen, "Surface-enhanced Raman spectroscopy of urine by an ingenious near-infrared Raman spectrometer", Proc. SPIE 6826, Optics in Health Care and Biomedical Optics III, 682628 (8 January 2008); doi: 10.1117/12.756716; https://doi.org/10.1117/12.756716
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