4 January 2008 Evaluation of fiber coupling coefficient by a deformed cell in dual-beam optical stretcher
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The dual-beam fiber-optic stretcher has been used for studying cell's viscoelastic properties under optical radiation pressure [1, 2]. In this paper we study the coupling from one fiber to another by a Red Blood Cell swollen to a spherical shape, and captured by the two countpropagating laser beams. First, we compute the photonics force distribution on the cell's surface using the ray optics, and then the deformation of the cell using the mechanics of the linear membrane theory of thin shell. Finally, we compute the coupling coefficient between the two fibers by the deformed ball lens of ellipsoidal shape. As the cell acts as a thick lens here, its spherical and defocus aberrations are estimated and included in the calculation of the coupling coefficient [3]. This technique could allow obtaining the visco-elasticity of a large number of cells by rapidly measuring the light coupling efficiency as a function of the laser beam power and the fiber end-to-fiber end separation, but without imaging and measuring the cells deformation.
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Paul Brule-Bareil, Paul Brule-Bareil, Yunlong Sheng, Yunlong Sheng, "Evaluation of fiber coupling coefficient by a deformed cell in dual-beam optical stretcher", Proc. SPIE 6832, Holography and Diffractive Optics III, 68320L (4 January 2008); doi: 10.1117/12.754723; https://doi.org/10.1117/12.754723

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