12 February 2008 A 3D dose model for low level laser / led therapy biostimulation and bioinhibition
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Abstract
There have been numerous reports describing the phenomena of biostimulation and bioinhibition using low-level laser therapy (LLLT) and other light and IR sources within the laboratory and in clinical trials. Stimulation or inhibition employed correctly has been shown clinically to reduce pain, improve tissue repair, resolve inflammation and stimulate the immune system. All these effects are sensitive to different irradiance and / or different energy (sometimes described as dose rate or fluence rate effects). The typical ranges for biostimulation and bioinhibition will be examined and a 3D Arndt Schulz style model proposed to illustrate possible 'dose sweet spots' for the intended clinical effects.
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James D. Carroll, James D. Carroll, } "A 3D dose model for low level laser / led therapy biostimulation and bioinhibition", Proc. SPIE 6846, Mechanisms for Low-Light Therapy III, 684603 (12 February 2008); doi: 10.1117/12.771183; https://doi.org/10.1117/12.771183
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