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5 March 2008 Segmentation of the retinal pigment epithelium by polarization sensitive optical coherence tomography
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Abstract
We report on a new method for segmenting the retinal pigment epithelium (RPE) in polarization sensitive optical coherence tomography (PS-OCT) images of the human retina. Contrary to previous segmentation algorithms that were based on variations of backscattered intensity between individual layers, our method uses an intrinsic tissue property of the RPE: its depolarizing, or polarization scrambling effect on backscattered light. By using a state of the art spectral domain PS-OCT instrument, we demonstrate the method in healthy eyes and in eyes of patients with age related macular degeneration.
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Christoph K. Hitzenberger, Erich Götzinger, Michael Pircher, Bernhard Baumann, Stephan Michels, Wolfgang Geitzenauer, and Ursula Schmidt-Erfurth "Segmentation of the retinal pigment epithelium by polarization sensitive optical coherence tomography", Proc. SPIE 6847, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII, 684705 (5 March 2008); https://doi.org/10.1117/12.761177
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