Automated method for RNFL segmentation in spectral domain OCT

Amit S. Paranjape; Badr Elmaanaoui; Jordan Dewelle; H. Grady Rylander; Thomas E. Milner

doi:10.1117/12.763491

12 February 2008 Automated method for RNFL segmentation in spectral domain OCT

Amit S. Paranjape, Badr Elmaanaoui, Jordan Dewelle, H. Grady Rylander, Thomas E. Milner

Proceedings Volume 6848, Advanced Biomedical and Clinical Diagnostic Systems VI; 68480N (2008) https://doi.org/10.1117/12.763491
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

We introduce a method based on optical reflectivity changes to segment the retinal nerve fiber layer (RNFL) in images recorded using swept source spectral domain optical coherence tomography (OCT). The segmented image is used to determine the RNFL thickness. Simple filtering followed by edge detecting techniques can successfully be applied to segment the RNFL from recorded images and estimate RNFL thickness. The method is computationally more efficient than previously reported approaches. Higher computational efficiency allows faster segmentation and provides the ophthalmologist segmented retinal images that better utilize advantages of spectral domain OCT instrumentation. OCT B-scan and fundus images of the retina are recorded for 5 patients. The segmentation method is applied on B-scan images recorded from all patients. An expert ophthalmologist separately demarcates the RNFL layer in the OCT images from the same patients in each B-scan image. Results from automated image processing software are compared to the boundary demarcated by the expert ophthalmologist. The absolute error between the boundaries demarcated by the expert and the algorithm is expressed in terms of area and is used as an error metric. Ability of the algorithm to accurately segment the RNFL in comparison with an expert ophthalmologist is reported.

Citation Download Citation

Amit S. Paranjape, Badr Elmaanaoui, Jordan Dewelle, H. Grady Rylander, and Thomas E. Milner "Automated method for RNFL segmentation in spectral domain OCT", Proc. SPIE 6848, Advanced Biomedical and Clinical Diagnostic Systems VI, 68480N (12 February 2008); https://doi.org/10.1117/12.763491

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