12 February 2008 Implementation of a VIS/NIR 3D hyperspectral instrument for in vivo imaging
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A novel application of hyperspectral instrumentation is described here, where a sheet-of-light method, produced by a low power laser light, is used to compute range measurements, and a hyperspectral instrument is used to acquire spectral information in the visible and near-infrared range of the spectrum. This report addresses two problems which in the literature are generally addressed independently; acquisition and analysis of hyperspectral images, and acquisition and analysis of range information. The bimodal instrument described in this report consists of a LCTF-based hyperspectral system which is used to acquire spectral images in the 450-1100 nm range and a multi-line laser light used to acquire range measurements of a scene. This laser light method can be used to acquire fast range measurements as the scene is partitioned into three sub-ranges therefore reducing the acquisition time by threefold. The methods used to get calibrated hyperspectral measurements (to reflectance values) of the proposed 3D hyperspectral instrument, and range measurements (to mm) are described in this paper. A test case shows the capabilities of this instrument for producing 3D hyperspectral imagery of human skin samples.
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Hector Erives, Hector Erives, Scott W. Teare, Scott W. Teare, Nicholas B. Targhetta, Nicholas B. Targhetta, } "Implementation of a VIS/NIR 3D hyperspectral instrument for in vivo imaging", Proc. SPIE 6850, Multimodal Biomedical Imaging III, 68500O (12 February 2008); doi: 10.1117/12.760552; https://doi.org/10.1117/12.760552

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