Improvement of performances in time-domain breast DOT by the aid of image segmentation

Yiwen Ma; Shaorun Gong; Feng Gao; Fang Yang; Huijuan Zhao; Jingying Jiang

doi:10.1117/12.762219

12 February 2008 Improvement of performances in time-domain breast DOT by the aid of image segmentation

Yiwen Ma, Shaorun Gong, Feng Gao, Fang Yang, Huijuan Zhao, Jingying Jiang

Proceedings Volume 6850, Multimodal Biomedical Imaging III; 68500P (2008) https://doi.org/10.1117/12.762219
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

The investigations on the optical mammography have attracted many clinical attentions, since the conventional X-ray mammography has shown some deficiencies in sensitivity, specificity, security and comfortableness. In this study, we propose an image reconstruction technique of time-domain diffuse optical tomography (DOT) for the optical mammography in the first place. This technique uses the finite-element method (FEM) solution to the Laplace-transformed coupled diffusion equations as the forward model, and develops an inverse model based on a Newton-Raphson scheme. On the basis of the preliminary reconstructed image of this technique, we also present an efficient Jacobian reduction method by the aid of image segmentation to obtain a more accurate image reconstruction. The simulative experiments reveal that the performance of reconstructed image by the aid of the image segmentation makes a notable improvement on the conventional algorithm in breast phantom image.

Citation Download Citation

Yiwen Ma, Shaorun Gong, Feng Gao, Fang Yang, Huijuan Zhao, and Jingying Jiang "Improvement of performances in time-domain breast DOT by the aid of image segmentation", Proc. SPIE 6850, Multimodal Biomedical Imaging III, 68500P (12 February 2008); https://doi.org/10.1117/12.762219

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