12 February 2008 Improvement of performances in time-domain breast DOT by the aid of image segmentation
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The investigations on the optical mammography have attracted many clinical attentions, since the conventional X-ray mammography has shown some deficiencies in sensitivity, specificity, security and comfortableness. In this study, we propose an image reconstruction technique of time-domain diffuse optical tomography (DOT) for the optical mammography in the first place. This technique uses the finite-element method (FEM) solution to the Laplace-transformed coupled diffusion equations as the forward model, and develops an inverse model based on a Newton-Raphson scheme. On the basis of the preliminary reconstructed image of this technique, we also present an efficient Jacobian reduction method by the aid of image segmentation to obtain a more accurate image reconstruction. The simulative experiments reveal that the performance of reconstructed image by the aid of the image segmentation makes a notable improvement on the conventional algorithm in breast phantom image.
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Yiwen Ma, Yiwen Ma, Shaorun Gong, Shaorun Gong, Feng Gao, Feng Gao, Fang Yang, Fang Yang, Huijuan Zhao, Huijuan Zhao, Jingying Jiang, Jingying Jiang, } "Improvement of performances in time-domain breast DOT by the aid of image segmentation", Proc. SPIE 6850, Multimodal Biomedical Imaging III, 68500P (12 February 2008); doi: 10.1117/12.762219; https://doi.org/10.1117/12.762219

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