20 February 2008 Full path Monte Carlo simulation of fluorescence in non-voxelized complex heterogeneous mouse model
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Abstract
In this article we propose an approach to improve the Monte Carlo simulation accuracy by implementing a full photon path integration simulation in a non-voxelized complex three-dimensional heterogeneous model. Mouse body shape, organs optical heterogeneities and fluorophore distribution are simulated by using boundary surface elements and basic analytical shapes. In addition, external and internal surface roughness and refractive index mismatch for complex angular objects are also considered and results are briefly compared with time sampled space voxelized Monte Carlo code, in order to illustrate the impact of these improvements on the simulation results.
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Jean-Francois Delorme, Jean-Francois Delorme, Guobin Ma, Guobin Ma, Frederic Lesage, Frederic Lesage, Frederic Leblond, Frederic Leblond, Anader Benyamin-Seyar, Anader Benyamin-Seyar, } "Full path Monte Carlo simulation of fluorescence in non-voxelized complex heterogeneous mouse model", Proc. SPIE 6854, Optical Interactions with Tissue and Cells XIX, 68541M (20 February 2008); doi: 10.1117/12.760822; https://doi.org/10.1117/12.760822
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