6 February 2008 New prospects for noninvasive blood monitoring based on effect of RBC aggregation
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Our analysis of spectral behavior of time-variant optical characteristics caused by RBC aggregation is applied to issues of non-invasive blood monitoring. Modulations of blood flow cause the change in geometry of RBC aggregates and corresponding variance of light scattering. This changes cause the variation of optical transmission, reflection, and polarization of outcoming light. The last can be translated back in absorption coefficients of various blood constituents, refractive index mismatch, etc. For instance, in case of long occlusion simultaneous measurements of both the azimuthal angle and the ellipticity of outcoming light can provide sufficient data to determine the blood glucose.
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L. D. Shvartsman, L. D. Shvartsman, I. Fine, I. Fine, D. A. Romanov, D. A. Romanov, } "New prospects for noninvasive blood monitoring based on effect of RBC aggregation", Proc. SPIE 6855, Complex Dynamics and Fluctuations in Biomedical Photonics V, 68550C (6 February 2008); doi: 10.1117/12.763066; https://doi.org/10.1117/12.763066

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