Simultaneous reconstruction of speed-of-sound and optical absorption properties in photoacoustic tomography via a time-domain iterative algorithm

Jin Zhang; Kun Wang; Yongyi Yang; Mark A. Anastasio

doi:10.1117/12.764171

28 February 2008 Simultaneous reconstruction of speed-of-sound and optical absorption properties in photoacoustic tomography via a time-domain iterative algorithm

Jin Zhang, Kun Wang, Yongyi Yang, Mark A. Anastasio

Author Affiliations +

Proceedings Volume 6856, Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics; 68561F (2008) https://doi.org/10.1117/12.764171
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

Photoacoustic tomography (PAT) is a hybrid imaging modality that combines the advantages of both optical imaging and ultrasound imaging techniques. Most existing reconstruction algorithms assume the speed-of-sound distribution within the object is homogeneous. In certain practical applications, this assumption may not be valid and will result in conspicuous image artifacts. In this work, we investigate the possibility of simultaneously estimating the speed-of-sound and optical absorption properties from data acquired in a PAT experiment. We propose and numerically implement a time-domain iterative algorithm that can reconstruct both the speed-of-sound and optical absorption distribution, by use of a priori information regarding the geometry of the speed-of-sound map. Computer-simulation results are presented to demonstrate the efficacy of the proposed reconstruction method.

Citation Download Citation

Jin Zhang, Kun Wang, Yongyi Yang, and Mark A. Anastasio "Simultaneous reconstruction of speed-of-sound and optical absorption properties in photoacoustic tomography via a time-domain iterative algorithm", Proc. SPIE 6856, Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 68561F (28 February 2008); https://doi.org/10.1117/12.764171

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