Nanolaser spectroscopy for studying novel biomaterials

P. L. Gourley; D. Y. Sasaki; R. K. Naviaux

doi:10.1117/12.786937

29 February 2008 Nanolaser spectroscopy for studying novel biomaterials

P. L. Gourley, D. Y. Sasaki, R. K. Naviaux

Proceedings Volume 6859, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VI; 685914 (2008) https://doi.org/10.1117/12.786937
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

Recent semiconductor technology has reduced the size of a laser to the size of a biological cell or even a virus particle. By integrating these ultra small lasers with biological systems, it is possible to create micro-electrical mechanical systems (MEMS) devices that are rapidly finding new applications for chemical analysis, molecular detection, and health care.1-5 One is a nanolaser device that confines intense light into an extremely small interaction volume.6-10 The nanolaser has been integrated with a microfluidic chip and applied to assess novel biomaterials, cells, and organelles. Importantly, these biomaterials can be analyzed without time delays or difficulties associated with chemical fixing or fluorescent markers. With these advantages, nanolaser spectroscopy represents a powerful tool for the rapid analysis of bioparticles such as cells, organelles, vesicles, virions, and other bioparticles.

Citation Download Citation

P. L. Gourley, D. Y. Sasaki, and R. K. Naviaux "Nanolaser spectroscopy for studying novel biomaterials", Proc. SPIE 6859, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VI, 685914 (29 February 2008); https://doi.org/10.1117/12.786937

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available