18 March 2008 Contrast-enhanced dual-energy subtraction imaging using electronic spectrum-splitting and multi-prism x-ray lenses
Author Affiliations +
Abstract
Dual-energy subtraction imaging (DES) is a method to improve the detectability of contrast agents over a lumpy background. Two images, acquired at x-ray energies above and below an absorption edge of the agent material, are logarithmically subtracted, resulting in suppression of the signal from the tissue background and a relative enhancement of the signal from the agent. Although promising, DES is still not widely used in clinical practice. One reason may be the need for two distinctly separated x-ray spectra that are still close to the absorption edge, realized through dual exposures which may introduce motion unsharpness. In this study, electronic spectrum-splitting with a silicon-strip detector is theoretically and experimentally investigated for a mammography model with iodinated contrast agent. Comparisons are made to absorption imaging and a near-ideal detector using a signal-to-noise ratio that includes both statistical and structural noise. Similar to previous studies, heavy absorption filtration was needed to narrow the spectra at the expense of a large reduction in x-ray flux. Therefore, potential improvements using a chromatic multi-prism x-ray lens (MPL) for filtering were evaluated theoretically. The MPL offers a narrow tunable spectrum, and we show that the image quality can be improved compared to conventional filtering methods.
© (2008) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Erik Fredenberg, Erik Fredenberg, Björn Cederström, Björn Cederström, Mats Lundqvist, Mats Lundqvist, Carolina Ribbing, Carolina Ribbing, Magnus Åslund, Magnus Åslund, Felix Diekmann, Felix Diekmann, Robert Nishikawa, Robert Nishikawa, Mats Danielsson, Mats Danielsson, } "Contrast-enhanced dual-energy subtraction imaging using electronic spectrum-splitting and multi-prism x-ray lenses", Proc. SPIE 6913, Medical Imaging 2008: Physics of Medical Imaging, 691310 (18 March 2008); doi: 10.1117/12.770501; https://doi.org/10.1117/12.770501
PROCEEDINGS
12 PAGES


SHARE
Back to Top