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18 March 2008 Using mastectomy specimens to develop breast models for breast tomosynthesis and CT breast imaging
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Abstract
Dedicated x-ray computed tomography (CT) of the breast using a cone-beam flat-panel detector system is a modality under investigation by a number of research teams. As previously reported, we have fabricated a prototype, bench-top flat-panel CT breast imaging (CTBI) system and developed computer simulation software to model such a system. We are developing a methodology to use high resolution, low noise CT reconstructions of fresh mastectomy specimens for generating an ensemble of 3D digital breast phantoms that realistically model 3D compressed and uncompressed breast anatomy. These breast models can be used to simulate realistic projection data for both breast tomosynthesis (BT) and CT systems thereby providing a powerful evaluation and optimization mechanism.
© (2008) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
J. Michael O'Connor, Mini Das, Clay Didier, Mufeed Mah'D, and Stephen J. Glick "Using mastectomy specimens to develop breast models for breast tomosynthesis and CT breast imaging", Proc. SPIE 6913, Medical Imaging 2008: Physics of Medical Imaging, 691315 (18 March 2008); https://doi.org/10.1117/12.772666
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