12 March 2008 Quantification of carotid arteries atherosclerosis using 3D ultrasound images and area-preserving flattened maps
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Abstract
Quantitative measurements of the progression (or regression) of carotid plaque burden are important in monitoring patients and evaluating new treatment options. 3D ultrasound (US) has been used to monitor the progression of carotid artery plaques in symptomatic and asymptomatic patients. Different methods of measuring various ultrasound phenotypes of atherosclerosis have been developed. In this work, we extended concepts used in intima-media thickness (IMT) measurements based on 2D images and introduced a metric called 3D vessel-wall-plus-plaque thickness (3D VWT), which was obtained by computing the distance between the carotid wall and lumen surfaces on a point-by-point basis in a 3D image of the carotid arteries. The VWT measurements were then superimposed on the arterial wall to produce the VWT map. Since the progression of plaque thickness is important in monitoring patients who are at risk for stroke, we also computed the change of VWT by comparing the VWT maps obtained for a patient at two different time points. In order to facilitate the visualization and interpretation of the 3D VWT and VWT-Change maps, we proposed a technique to flatten these maps in an area-preserving manner.
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Bernard Chiu, Bernard Chiu, Micaela Egger, Micaela Egger, J. David Spence, J. David Spence, Grace Parraga, Grace Parraga, Aaron Fenster, Aaron Fenster, } "Quantification of carotid arteries atherosclerosis using 3D ultrasound images and area-preserving flattened maps", Proc. SPIE 6916, Medical Imaging 2008: Physiology, Function, and Structure from Medical Images, 691603 (12 March 2008); doi: 10.1117/12.770359; https://doi.org/10.1117/12.770359
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