Circumferential strain of the left ventricle reflects myocardial contractility and is considered a key index of
cardiac function. It is also an important parameter in the quantitative evaluation of heart failure.
Circumferential compression encoding, CIRCOME, is a novel method in cardiac MRI to evaluate this strain
non-invasively and quickly. This strain encoding technique avoids the explicit measurement of the
displacement field and does not require calculation of strain through spatial differentiation. CIRCOME
bypasses these two time-consuming and noise sensitive steps by directly using the frequency domain (k-space)
information from radially tagged myocardium, before and after deformation. It uses the ring-shaped
crown region of the k-space, generated by the taglines, to reconstruct circumferentially compression-weighted
images of the heart before and after deformation. CIRCOME then calculates the circumferential
strain through relative changes in the compression level of corresponding regions before and after
deformation. This technique can be implemented in 3D as well as 2D and may be employed to estimate the
overall global or regional circumferential strain. The main parameters that affect the accuracy of this method
are spatial resolution, signal to noise ratio, eccentricity of the center of radial taglines their fading and their
density. Also, a variety of possible image reconstruction and filtering options may influence the accuracy of
the method. This study describes the pulse sequence, algorithm, influencing factors and limiting criteria for
CIRCOME and provides the simulated results.