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10 March 2008 Measurement of thermally ablated lesions in sonoelastographic images using level set methods
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The capability of sonoelastography to detect lesions based on elasticity contrast can be applied to monitor the creation of thermally ablated lesion. Currently, segmentation of lesions depicted in sonoelastographic images is performed manually which can be a time consuming process and prone to significant intra- and inter-observer variability. This work presents a semi-automated segmentation algorithm for sonoelastographic data. The user starts by planting a seed in the perceived center of the lesion. Fast marching methods use this information to create an initial estimate of the lesion. Subsequently, level set methods refine its final shape by attaching the segmented contour to edges in the image while maintaining smoothness. The algorithm is applied to in vivo sonoelastographic images from twenty five thermal ablated lesions created in porcine livers. The estimated area is compared to results from manual segmentation and gross pathology images. Results show that the algorithm outperforms manual segmentation in accuracy, inter- and intra-observer variability. The processing time per image is significantly reduced.
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Benjamin Castaneda, Jose Gerardo Tamez-Pena, Man Zhang, Kenneth Hoyt, Kevin Bylund, Jared Christensen, Wael Saad, John Strang, Deborah J. Rubens, and Kevin J. Parker "Measurement of thermally ablated lesions in sonoelastographic images using level set methods", Proc. SPIE 6920, Medical Imaging 2008: Ultrasonic Imaging and Signal Processing, 692018 (10 March 2008);

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