15 April 2008 Point detection of bacterial and viral pathogens using oral samples
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Abstract
Oral samples, including saliva, offer an attractive alternative to serum or urine for diagnostic testing. This is particularly true for point-of-use detection systems. The various types of oral samples that have been reported in the literature are presented here along with the wide variety of analytes that have been measured in saliva and other oral samples. The paper focuses on utilizing point-detection of infectious disease agents, and presents work from our group on a rapid test for multiple bacterial and viral pathogens by monitoring a series of targets. It is thus possible in a single oral sample to identify multiple pathogens based on specific antigens, nucleic acids, and host antibodies to those pathogens. The value of such a technology for detecting agents of bioterrorism at remote sites is discussed.
© (2008) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Daniel Malamud, Daniel Malamud, } "Point detection of bacterial and viral pathogens using oral samples", Proc. SPIE 6945, Optics and Photonics in Global Homeland Security IV, 69450C (15 April 2008); doi: 10.1117/12.779160; https://doi.org/10.1117/12.779160
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