Nanophotonics bio-sensor using gold nanostructure

Masayuki Naya; Takeharu Tani; Yuichi Tomaru; Jingbo Li; Naoki Murakami

doi:10.1117/12.800900

26 August 2008 Nanophotonics bio-sensor using gold nanostructure

Masayuki Naya, Takeharu Tani, Yuichi Tomaru, Jingbo Li, Naoki Murakami

Proceedings Volume 7032, Plasmonics: Metallic Nanostructures and Their Optical Properties VI; 70321Q (2008) https://doi.org/10.1117/12.800900
Event: NanoScience + Engineering, 2008, San Diego, California, United States

Abstract

As a bio-molecular-sensor with high sensitivity using surface-enhanced Raman scattering (SERS), we developed two dimensional gold nano-mushroom arrays (G-NAMS). Because the heads of the gold mushrooms are closely placed over all aspects on a surface of substrate, a lot of SERS enable spot, so called "hot spots", are formed. . By using G-NAMS, we observed Raman signals of some bio samples. In the experiment to observe the adenine, which is one of four basis of the gene, dissolved in PBS solution, adenine concentrations of 5 pM could be detected. FDTD simulation indicated, that strong Raman enhancement of G-NAMS occurs due to synergistic action of the hot spots produced between metal nanoparticles, and the optical resonant effect in the alumina layer.

Citation Download Citation

Masayuki Naya, Takeharu Tani, Yuichi Tomaru, Jingbo Li, and Naoki Murakami "Nanophotonics bio-sensor using gold nanostructure", Proc. SPIE 7032, Plasmonics: Metallic Nanostructures and Their Optical Properties VI, 70321Q (26 August 2008); https://doi.org/10.1117/12.800900

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