29 August 2008 Wireless integrated microsystems for monitoring brain chemical and electrical activity
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Proceedings Volume 7035, Biosensing; 70350O (2008) https://doi.org/10.1117/12.796007
Event: NanoScience + Engineering, 2008, San Diego, California, United States
Abstract
A 16-channel chip for wireless in vivo recording of chemical and electrical neural activity is described. The 7.83-mm2 IC is fabricated using a 0.5-μm CMOS process and incorporates a 71-μW, 3rd-order, reconfigurable, ΔΣ modulator per channel, achieving an input-referred noise of 4.69 μVrms in 4-kHz BW and 94.1 pArms in 5-kHz BW for electrical and fast-scan voltammetric chemical neurosensing, respectively. The chip has been externally interfaced with carbon-fiber microelectrodes implanted acutely in the caudate-putamen of an anesthetized rat, and, for the first time, extracellular levels of dopamine elicited by electrical stimulation of the medial forebrain bundle have been successfully recorded wirelessly across multiple channels using 300-V/s fast-scan cyclic voltammetry.
© (2008) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Masoud Roham, Masoud Roham, Paul A. Garris, Paul A. Garris, Pedram Mohseni, Pedram Mohseni, } "Wireless integrated microsystems for monitoring brain chemical and electrical activity", Proc. SPIE 7035, Biosensing, 70350O (29 August 2008); doi: 10.1117/12.796007; https://doi.org/10.1117/12.796007
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