16 September 2008 Advances in the visualization of unstained brain tumors using grating-based x-ray phase-contrast tomography
Author Affiliations +
Abstract
We report advances and complementary results concerning a recently developed method for high-sensitivity grating-based hard x-ray phase tomography. We demonstrate how the soft tissue sensitivity of the technique can be used to obtain in-vitro tomographic images of a tumor bearing rat brain specimen, without use of contrast agents. In particular, we demonstrate that brain tumors and the white and gray brain matter structure in a rat's cerebellum can be resolved by this approach. The findings are potentially interesting from a clinical point of view, since a similar approach using three transmission gratings can be implemented with more readily available x-ray sources, such as standard x-ray tubes. Moreover, open the results the way to in-vivo experiments in the near future.
© (2008) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Franz Pfeiffer, Franz Pfeiffer, Oliver Bunk, Oliver Bunk, Christian David, Christian David, Martin Bech, Martin Bech, Geraldine Le Duc, Geraldine Le Duc, Alberto Bravin, Alberto Bravin, Peter Cloetens, Peter Cloetens, } "Advances in the visualization of unstained brain tumors using grating-based x-ray phase-contrast tomography", Proc. SPIE 7078, Developments in X-Ray Tomography VI, 707815 (16 September 2008); doi: 10.1117/12.794666; https://doi.org/10.1117/12.794666
PROCEEDINGS
10 PAGES


SHARE
Back to Top