Bio-security for health monitoring and diagnosis are the needs of the hour, for rapid detection of biological and chemical
species. This calls for a necessity to develop a cost effective miniaturized and portable biosensor device for in-situ
biomedical applications and Point-of-Care Testing (POCT). While portability of the biosensor is required for in-situ
medical detections, miniaturization is essential for handling smaller sample volumes and high throughput. Thus, the
above mentioned concerns cannot be addressed unless a fully integrated biosensor system is developed. In this work, an
integrated opto microfluidic based Lab-on-a-chip device is proposed for carrying out fluorescence based biodetection.
The input and output fibers were integrated with the microfluidic channel so as to make a robust setup. Fluorescence
detection was carried out using Alexafluor 647 tagged antibody particles and the output was measured with a
Spectrometer-on-Chip, integrated with the device. The experimental results prove that the proposed device is highly
suitable for Lab-on-a-Chip applications.