12 August 2008 Integrated optical microfluidic lab-on-a-chip
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Proceedings Volume 7099, Photonics North 2008; 70992B (2008) https://doi.org/10.1117/12.807550
Event: Photonics North 2008, 2008, Montréal, Canada
Abstract
Bio-security for health monitoring and diagnosis are the needs of the hour, for rapid detection of biological and chemical species. This calls for a necessity to develop a cost effective miniaturized and portable biosensor device for in-situ biomedical applications and Point-of-Care Testing (POCT). While portability of the biosensor is required for in-situ medical detections, miniaturization is essential for handling smaller sample volumes and high throughput. Thus, the above mentioned concerns cannot be addressed unless a fully integrated biosensor system is developed. In this work, an integrated opto microfluidic based Lab-on-a-chip device is proposed for carrying out fluorescence based biodetection. The input and output fibers were integrated with the microfluidic channel so as to make a robust setup. Fluorescence detection was carried out using Alexafluor 647 tagged antibody particles and the output was measured with a Spectrometer-on-Chip, integrated with the device. The experimental results prove that the proposed device is highly suitable for Lab-on-a-Chip applications.
© (2008) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Arvind Chandrasekaran, Muthukumaran Packirisamy, "Integrated optical microfluidic lab-on-a-chip", Proc. SPIE 7099, Photonics North 2008, 70992B (12 August 2008); doi: 10.1117/12.807550; https://doi.org/10.1117/12.807550
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