30 December 2008 Nanoparticles for enhanced contrast optical coherence tomography
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Proceedings Volume 7139, 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics; 71390V (2008) https://doi.org/10.1117/12.818690
Event: 1st Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics, 2008, Canterbury, United Kingdom
Abstract
Recently the area of bioimaging has benefited from new types of image enhancing agents such as quantum dots, carbon nanotubes and other nanoparticles. Cellular or even molecular level resolution has been achieved with different techniques during these last years (i.a. Fluorescence microscopy, PET/CT scan, AFM). Optical Coherence Tomography (OCT) as an imaging technique should also profit from newly developed probes. In this work we explored the tunable properties of different types of nanoparticles as contrast enhancers in OCT applications. We mainly studied the development and characteristics of metallic nanoparticles with tunable properties: gold nanoshells made of a silica core coated with a gold shell. Nanoshell and nanoparticles processing techniques are discussed, as well as their optimization for designing particles with specific absorption and scattering characteristics, and its use in OCT imaging.
© (2008) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
César D. Maule, César D. Maule, Pedro Quaresma, Pedro Quaresma, Patrícia A. Carvalho, Patrícia A. Carvalho, Pedro Jorge, Pedro Jorge, Eulália Pereira, Eulália Pereira, Carla C. Rosa, Carla C. Rosa, } "Nanoparticles for enhanced contrast optical coherence tomography", Proc. SPIE 7139, 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics, 71390V (30 December 2008); doi: 10.1117/12.818690; https://doi.org/10.1117/12.818690
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