2 December 2008 Micro-Raman scattering and infrared spectra of hemoglobin
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Proceedings Volume 7142, Sixth International Conference on Advanced Optical Materials and Devices (AOMD-6); 714214 (2008) https://doi.org/10.1117/12.815796
Event: Sixth International Conference on Advanced Optical Materials and Devices, 2008, Riga, Latvia
Abstract
Confocal micro-Raman and FT-IR spectroscopies have been used for detection of radiation influence of hemoglobin of patients examined by radio-isotopes diagnosis (Tc99m). After irradiation we observed some little changes of the Raman scattering bands which connected with out of plane porphyrine bending vibrations, also we observed additional band due to methemoglobin. Radiation of blood lead to the transition from hemoglobin (Fe2+) to methemoglobin (Fe3+) with a delocalization of iron from porphyrine plane. It was shown that FT-IR spectra indicate the radiation effects on hemoglobin.
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M. Polakovs, M. Polakovs, N. Mironova-Ulmane, N. Mironova-Ulmane, N. Kurjane, N. Kurjane, E. Reinholds, E. Reinholds, M. Grube, M. Grube, } "Micro-Raman scattering and infrared spectra of hemoglobin", Proc. SPIE 7142, Sixth International Conference on Advanced Optical Materials and Devices (AOMD-6), 714214 (2 December 2008); doi: 10.1117/12.815796; https://doi.org/10.1117/12.815796
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