23 February 2009 In vivo office-based dynamic imaging of vocal cords in awake patients with swept-source optical coherence tomography
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Abstract
Optical coherence tomography (OCT) is an evolving noninvasive imaging modality and has been used to image the human larynx during surgical endoscopy. The design of a long GRIN lens based probe capable of capturing images of the human larynx by use of swept-source OCT during a typical office-based laryngoscopy examination is presented. In vivo OCT imaging of the human larynx is demonstrated with 40 fame/second. Dynamic vibration of the vocal folds is recorded to provide not only high-resolution cross-sectional tissue structures but also vibration parameters, such as the vibration frequency and magnitude of the vocal cord, which provide important information for clinical diagnosis and treatment, as well as in fundamental research of the voice. Office-based OCT is a promising imaging modality to study the larynx.
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Lingfeng Yu, Gangjun Liu, Marc Rubinstein, Arya Saidi, Shuguang Guo, Brian J. F. Wong, Zhongping Chen, "In vivo office-based dynamic imaging of vocal cords in awake patients with swept-source optical coherence tomography", Proc. SPIE 7161, Photonic Therapeutics and Diagnostics V, 716126 (23 February 2009); doi: 10.1117/12.823466; https://doi.org/10.1117/12.823466
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