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23 February 2009 Computational model of retinal photocoagulation and rupture
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Proceedings Volume 7163, Ophthalmic Technologies XIX; 71630T (2009)
Event: SPIE BiOS, 2009, San Jose, California, United States
In patterned scanning laser photocoagulation, shorter duration (< 20 ms) pulses help reduce thermal damage beyond the photoreceptor layer, decrease treatment time and minimize pain. However, safe therapeutic window (defined as the ratio of rupture threshold power to that of light coagulation) decreases for shorter exposures. To quantify the extent of thermal damage in the retina, and maximize the therapeutic window, we developed a computational model of retinal photocoagulation and rupture. Model parameters were adjusted to match measured thresholds of vaporization, coagulation, and retinal pigment epithelial (RPE) damage. Computed lesion width agreed with histological measurements in a wide range of pulse durations and power. Application of ring-shaped beam profile was predicted to double the therapeutic window width for exposures in the range of 1 - 10 ms.
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Christopher Sramek, Yannis M. Paulus, Hiroyuki Nomoto, Phil Huie, and Daniel Palanker "Computational model of retinal photocoagulation and rupture", Proc. SPIE 7163, Ophthalmic Technologies XIX, 71630T (23 February 2009);

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