23 February 2009 Photochemical effects in the lens from near infrared radiation?
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Proceedings Volume 7163, Ophthalmic Technologies XIX; 716311 (2009); doi: 10.1117/12.816848
Event: SPIE BiOS, 2009, San Jose, California, United States
Abstract
Conclusion: The current data are consistent with a potential photochemical effect of in vivo exposure of the crystalline lens to near infrared radiation since the onset of cataract after in just above threshold dose was at least 18 hrs delayed after the exposure. Materials and methods: The eyes of 6 weeks old Sprague-Dawley rats were exposed unilaterally in vivo to 1090 nm, 6.2 W quasi-top hat spatial distribution with a 3 mm spot on the anterior lens surface within the dilated pupil. First, four exposure time groups of rats were exposed to increasing exposure times. At 24 hrs after exposure, the difference of light scattering between the lenses from the same animal was measured. Then, based on the first experiment, four post-exposure time groups were exposed unilaterally in vivo to 8 s of 1090 nm, 6.2 W quasi-top hat spatial distribution with a 3 mm spot on the anterior lens surface within the dilated pupil. After, the intended post-exposure time, the difference of light scattering between the lenses from the same animal was measured. Results: A 3 mm spot of 6.2 W induces light scattering in the lens with exposures of at least 8 s. Further, after 8 s of 6.2 W within a 3 mm spot on the lens surface, the light scattering increase in the lens was delayed at least 18 hrs after the exposure.
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Per G. Söderberg, Riyadh Al-Saqry, Karl Schulmeister, Konstantin Gallichanin, Martin Kronschläger, Zhaohua Yu, "Photochemical effects in the lens from near infrared radiation?", Proc. SPIE 7163, Ophthalmic Technologies XIX, 716311 (23 February 2009); doi: 10.1117/12.816848; http://dx.doi.org/10.1117/12.816848
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KEYWORDS
Light scattering

In vivo imaging

Near infrared

Eye

Cornea

Crystals

Optical testing

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