19 February 2009 Enhancing lab-on-a-chip performance via tunable parallel liquid mircolens arrays
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Abstract
We report an in situ formed tunable liquid microlense array and its applications for enhancing dynamic lab-on-a-chip performance. The de-ionized water microlenses are intrinsically formed via liquid-air interfaces of liquid droplets at T-shaped junctions of octadecyltrichlorosilane(OTS) treated polymerized isobornyl acrylate(poly(IBA)) microchannels., and can be separately tuned in focal lengths by pneumatic manipulation. Via the tunable microlenses, excitation light is dynamically focused onto the fluorescent fluidic sample, thus the fluorescence emission signal for detection is amplified. We have further shown the potential for surface reaction study at microfluidic interfaces by the microlense array.
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Ye Liu, Xuefeng Zeng, Liang Dong, Hongrui Jiang, "Enhancing lab-on-a-chip performance via tunable parallel liquid mircolens arrays", Proc. SPIE 7167, Frontiers in Pathogen Detection: From Nanosensors to Systems, 71670L (19 February 2009); doi: 10.1117/12.809588; https://doi.org/10.1117/12.809588
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