23 February 2009 Protein profile study of clinical samples using laser induced fluorescence as the detection method: case of malignant and normal cervical tissues
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Abstract
Protein profiles of tissue homogenates were recorded using HPLC separation and LIF detection method. The samples were collected from volunteers with clinically normal or cervical cancer conditions. It is shown that the protein profile can be classified as belonging to malignant or normal state by using hard and Fuzzy clustering methods. The study was performed to test the utility of the HPLC-LIF protein profiling method for classification of tissue samples as well as to establish a complementary method for histopathology for clinical diagnosis of the tissue as normal or malignant.
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Gopal Karemore, Gopal Karemore, Sujatha N. Raja, Sujatha N. Raja, Lavanya Rai, Lavanya Rai, V. B. Kartha, V. B. Kartha, Santhosh Chidangil, Santhosh Chidangil, "Protein profile study of clinical samples using laser induced fluorescence as the detection method: case of malignant and normal cervical tissues", Proc. SPIE 7169, Advanced Biomedical and Clinical Diagnostic Systems VII, 71691I (23 February 2009); doi: 10.1117/12.809972; https://doi.org/10.1117/12.809972
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