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12 February 2009 Double layer estimation of flow changes using diffuse correlation spectroscopy
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Abstract
In this work, we explore diffuse correlation spectroscopy (DCS) in a two-layered geometry. We compare the effiency of an homogeneous and a two-layered model to recover flow changes. By simulating a realistic human head with MRI anatomical data, we show that the two-layered model allows distinction between superficial layers and brain hemodynamic changes. The results show that the two-layered model provides a better estimate for the flow change than the homogeneous one. Experimental measurements with a two-layered dynamical phantom confirm the ability of the two-layered analytical model to distinguish flow increase in each layer.
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Louis Gagnon, Michèle Desjardins, Louis Bherer, and Frédéric Lesage "Double layer estimation of flow changes using diffuse correlation spectroscopy", Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 717407 (12 February 2009); https://doi.org/10.1117/12.808272
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