12 February 2009 Spectroscopic technique with wide range of wavelength information improves near-infrared spectroscopy
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Near-infrared spectroscopy (NIRS) calculates hemoglobin parameters, such as oxygenated hemoglobin (oxyHb) and deoxygenated hemoglobin (deoxyHb) using the near-infrared light around the wavelength of 800nm. This is based on the modified-Lambert-Beer's law that changes in absorbance are proportional to changes in hemoglobin parameters. Many conventional measurement methods uses only a few wavelengths, however, in this research, basic examination of NIRS measurement was approached by acquiring wide range of wavelength information. Venous occlusion test was performed by using the blood pressure cuff around the upper arm. Pressure of 100mmHg was then applied for about 3 minutes. During the venous occlusion, the spectrum of the lower arm muscles was measured every 15 seconds, within the range of 600 to 1100nm. It was found that other wavelength bands hold information correlating to this venous occlusion task. Technique of improving the performance of NIRS measurement using the Spectroscopic Method is very important for Brain science.
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Hideo Eda, Hideo Eda, Hiromichi Aoki, Hiromichi Aoki, Shigeru Eura, Shigeru Eura, Kazutoshi Ebe, Kazutoshi Ebe, } "Spectroscopic technique with wide range of wavelength information improves near-infrared spectroscopy", Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 717409 (12 February 2009); doi: 10.1117/12.809177; https://doi.org/10.1117/12.809177

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