Relative capacities of time-gated versus CW imaging to localize tissue embedded vessels with increasing depth

George Alexandrakis; Nimit L. Patel; Zi-Jing Lin; Edward H. Livingston; Hanli Liu

doi:10.1117/12.807887

12 February 2009 Relative capacities of time-gated versus CW imaging to localize tissue embedded vessels with increasing depth

George Alexandrakis, Nimit L. Patel, Zi-Jing Lin, Edward H. Livingston, Hanli Liu

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Proceedings Volume 7174, Optical Tomography and Spectroscopy of Tissue VIII; 71740B (2009) https://doi.org/10.1117/12.807887
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

The clinical motivation for our work was to help surgeons see vessels through non-translucent intraoperative tissues during laparoscopic removal of the gallbladder. Our main focus was to answer the question of how CW imaging performs relative to ICCD (Intensified Charge-Coupled Device) based time-gated imaging, which is a lot more costly, under broad Gaussian beam illumination conditions. We have studied the simplified case of an isolated bile duct embedded at different depths within a 2 cm slab of adipose tissue. Monte Carlo simulations were preformed for both reflectance and trans-illumination geometries. The relative performance of CW versus time-gated imaging was compared in terms of spatial resolution and vessel detection sensitivity in the resulting simulated images. Experiments were performed in reflectance geometry to validate simulation results. It was found that time-gated imaging offers superior spatial resolution and vessel detection sensitivity in all cases though CW trans-illumination measurements may also offer satisfactory performance for this tissue geometry at a lower cost.

Citation Download Citation

George Alexandrakis, Nimit L. Patel, Zi-Jing Lin, Edward H. Livingston, and Hanli Liu "Relative capacities of time-gated versus CW imaging to localize tissue embedded vessels with increasing depth", Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 71740B (12 February 2009); https://doi.org/10.1117/12.807887

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KEYWORDS

Reflectivity

Monte Carlo methods

Tissues

Capillaries

Tissue optics

Cameras

Spatial resolution

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