23 February 2009 Functional brain tomography using a time-gated ICCD camera
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Abstract
The mean penetration depth of diffusely reflected photons is dependent on the arrival time t of photons, but not on the source-detector distance. Thus, all photons collected at the same t have the same depth sensitivity, and can be used for the reconstruction. Following this concept, we have implemented a system for 3D tomography using a single injection fiber and a time-gated ICCD camera. The feasibility of the novel approach to reconstruct a local perturbation was demonstrated both with simulations and phantom measurements. Finally, preliminary measurements were performed in vivo following a standard protocol of motor cortex activation.
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Antonio Pifferi, Antonio Pifferi, Qing Zhao, Qing Zhao, Lorenzo Spinelli, Lorenzo Spinelli, Andrea Bassi, Andrea Bassi, Gianluca Valentini, Gianluca Valentini, Davide Contini, Davide Contini, Rinaldo Cubeddu, Rinaldo Cubeddu, Alessandro Torricelli, Alessandro Torricelli, } "Functional brain tomography using a time-gated ICCD camera", Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 71741L (23 February 2009); doi: 10.1117/12.809690; https://doi.org/10.1117/12.809690
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