24 February 2009 Finite element model of thermal processes in retinal photocoagulation
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Abstract
Short duration (< 20 ms) pulses are desirable in patterned scanning laser photocoagulation to confine thermal damage to the photoreceptor layer, decrease overall treatment time and reduce pain. However, short exposures have a smaller therapeutic window (defined as the ratio of rupture threshold power to that of light coagulation). We have constructed a finite-element computational model of retinal photocoagulation to predict spatial damage and improve the therapeutic window. Model parameters were inferred from experimentally measured absorption characteristics of ocular tissues, as well as the thresholds of vaporization, coagulation, and retinal pigment epithelial (RPE) damage. Calculated lesion diameters showed good agreement with histological measurements over a wide range of pulse durations and powers.
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Christopher Sramek, Yannis M. Paulus, Hiroyuki Nomoto, Phil Huie, Daniel Palanker, "Finite element model of thermal processes in retinal photocoagulation", Proc. SPIE 7175, Optical Interactions with Tissue and Cells XX, 71751F (24 February 2009); doi: 10.1117/12.828888; https://doi.org/10.1117/12.828888
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