3D photoacoustic imaging of a moving target

Pinhas Ephrat; Michael Roumeliotis; Frank S. Prato; Jeffrey J. L. Carson

doi:10.1117/12.807878

24 February 2009 3D photoacoustic imaging of a moving target

Pinhas Ephrat, Michael Roumeliotis, Frank S. Prato, Jeffrey J. L. Carson

Proceedings Volume 7177, Photons Plus Ultrasound: Imaging and Sensing 2009; 71770W (2009) https://doi.org/10.1117/12.807878
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

We have developed a fast 3D photoacoustic imaging system based on a sparse array of ultrasound detectors and iterative image reconstruction. To investigate the high frame rate capabilities of our system in the context of rotational motion, flow, and spectroscopy, we performed high frame-rate imaging on a series of targets, including a rotating graphite rod, a bolus of methylene blue flowing through a tube, and hyper-spectral imaging of a tube filled with methylene blue under a no flow condition. Our frame-rate for image acquisition was 10 Hz, which was limited by the laser repetition rate. We were able to track the rotation of the rod and accurately estimate its rotational velocity, at a rate of 0.33 rotations-per-second. The flow of contrast in the tube, at a flow rate of 180 μL/min, was also well depicted, and quantitative analysis suggested a potential method for estimating flow velocity from such measurements. The spectrum obtained did not provide accurate results, but depicted the spectral absorption signature of methylene blue , which may be sufficient for identification purposes. These preliminary results suggest that our high frame-rate photoacoustic imaging system could be used for identifying contrast agents and monitoring kinetics as an agent propagates through specific, simple structures such as blood vessels.

Citation Download Citation

Pinhas Ephrat, Michael Roumeliotis, Frank S. Prato, and Jeffrey J. L. Carson "3D photoacoustic imaging of a moving target", Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71770W (24 February 2009); https://doi.org/10.1117/12.807878

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available