24 February 2009 Serum protein profile study of clinical samples using high performance liquid chromatography-laser induced fluorescence: case of cervical and oral cancers
Author Affiliations +
Proceedings Volume 7182, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII; 71820J (2009); doi: 10.1117/12.809930
Event: SPIE BiOS, 2009, San Jose, California, United States
Abstract
The serum protein profiles of normal subjects, patients diagnosed with cervical cancer, and oral cancer were recorded using High Performance Liquid Chromatography combined with Laser Induced Fluorescence detection (HPLC-LIF). Serum protein profiles of the above three classes were tested for establishing the ability of HPLC-LIF protein profiling technique for discrimination, using hard clustering and Fuzzy clustering methods. The clustering algorithms have quite successfully classified the profiles as belonging to normal, cancer of cervix, and oral cancer conditions.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Gopal Karemore, . Sujatha, Lavanya Rai, Keerthilatha M. Pai, V. B. Kartha, . Santhosh C., "Serum protein profile study of clinical samples using high performance liquid chromatography-laser induced fluorescence: case of cervical and oral cancers", Proc. SPIE 7182, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII, 71820J (24 February 2009); doi: 10.1117/12.809930; https://doi.org/10.1117/12.809930
PROCEEDINGS
9 PAGES


SHARE
KEYWORDS
Proteins

Cervical cancer

Cancer

Fuzzy logic

Principal component analysis

Associative arrays

Liquids

Back to Top