23 February 2009 Atmospheric pressure femtosecond laser imaging mass spectrometry
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Abstract
We present a novel imaging mass spectrometry technique that uses femtosecond laser pulses to directly ionize the sample. The method offers significant advantages over current techniques by eliminating the need of a laser-absorbing sample matrix, being suitable for atmospheric pressure sampling, and by providing 10μm resolution, as demonstrated here with a chemical image of vegetable cell walls.
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Yves Coello, Tissa C. Gunaratne, Marcos Dantus, "Atmospheric pressure femtosecond laser imaging mass spectrometry", Proc. SPIE 7182, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII, 71821W (23 February 2009); doi: 10.1117/12.808252; https://doi.org/10.1117/12.808252
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