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24 February 2009 Light scattering by ellipsoidal particles and Fourier analysis in the frequency domain
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Abstract
The study of biological tissue using white light spectroscopy has the potential to be an effective, fast, and inexpensive method for the detection of size changes in cell nuclei. The relationship between the spherical scatterer size and the number of oscillation peaks in the optical spectrum (intensity of scattered light versus wavelength) has been observed by many researchers. To this point, there was not a detailed theoretical model describing this dependence for elliptical particles, a common shape of cell nuclei at lower tissue layers. In this paper, we report a theoretical model, valid for both spheres and ellipsoids, detailing the scattering intensity as a function of the wavelength and the scatterer's diameter. Supporting this theory, we experimentally test mixtures of scatterers of different sizes and provide density analysis.
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Kaloyan A. Popov and Timothy P. Kurzweg "Light scattering by ellipsoidal particles and Fourier analysis in the frequency domain", Proc. SPIE 7187, Biomedical Applications of Light Scattering III, 718719 (24 February 2009); https://doi.org/10.1117/12.807938
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