Synthesis and exploitation of InP/ZnS quantum dots for bioimaging

Salam Massadeh; Shu Xu; Thomas Nann

doi:10.1117/12.816892

13 February 2009 Synthesis and exploitation of InP/ZnS quantum dots for bioimaging

Salam Massadeh, Shu Xu, Thomas Nann

Proceedings Volume 7189, Colloidal Quantum Dots for Biomedical Applications IV; 718902 (2009) https://doi.org/10.1117/12.816892
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Nano- and cytotoxicity becomes increasingly more important with an increasing number of potential bio-medical applications for semiconductor Quantum Dots (QDs). Therefore, the frequently used CdSe-based QDs are unsuitable per-se, since cadmium is a highly toxic heavy metal and may leach out of QDs. Cadmium-free QDs have not been available for a long time, because the synthesis of e.g. monodisperes and highly crystalline InP QDs caused many problems. We report on the synthesis of InP/ZnS QDs with optical properties similar to those displayed by typical CdSe/ZnS QDs. A major break-through has been reached by addition of zinc ions into the reaction mixture. Furthermore, the transfer of the InP/ZnS QDs to water and their exploitation for bioanalytical applications are reported. It is shown that InP/ZnS QDs can be used to replace CdSe-based ones for almost any bio-medical application.

Citation Download Citation

Salam Massadeh, Shu Xu, and Thomas Nann "Synthesis and exploitation of InP/ZnS quantum dots for bioimaging", Proc. SPIE 7189, Colloidal Quantum Dots for Biomedical Applications IV, 718902 (13 February 2009); https://doi.org/10.1117/12.816892

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