Comparative cytotoxicity of quantum dot and gold conjugates

Jay Nadeau; Anil Kumar; Eve-Marie Dumas

doi:10.1117/12.813592

3 March 2009 Comparative cytotoxicity of quantum dot and gold conjugates

Jay Nadeau, Anil Kumar, Eve-Marie Dumas

Proceedings Volume 7189, Colloidal Quantum Dots for Biomedical Applications IV; 718916 (2009) https://doi.org/10.1117/12.813592
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Nanoparticle toxicity is of interest for the design of anti-bacterial and anti-cancer agents, and also for development of regulations for their safe handling and disposal. However, the same reactivity that makes nanoparticles show unique optical properties also makes them interact with standard cytotoxicity agents, causing false positive and/or false negative results. We discuss which cytotoxicity assays are most likely to work with nanoparticles and which are to be avoided, and present some results on comparative cytotoxicity of different types of conjugates.

Citation Download Citation

Jay Nadeau, Anil Kumar, and Eve-Marie Dumas "Comparative cytotoxicity of quantum dot and gold conjugates", Proc. SPIE 7189, Colloidal Quantum Dots for Biomedical Applications IV, 718916 (3 March 2009); https://doi.org/10.1117/12.813592

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